Recently developed experimental and computational approaches to identify putative coding small ORFs (smORFs) in genomes have revealed thousands of smORFs localized within coding and non-coding RNAs.They can be translated into smORF peptides or microproteins, which Shorts are defined as less than 100 amino acids in length.The identification of such
Metabolic disorders such as type 2 diabetes cause hepatic endoplasmic reticulum (ER) stress, which affects neutral lipid metabolism.However, the role of Softball Jersey ER stress in cholesterol metabolism is incompletely understood.Here, we show that induction of acute ER stress in human hepatic HepG2 cells reduced ABCA1 expression and caused ABCA1
This work presents a lab-on-chip system, which combines a glass-polydimethilsiloxane microfluidic network and an array of amorphous silicon photosensors for the diagnosis and follow-up of Celiac disease.The microfluidic chip Stockings implements an on-chip enzyme-linked immunosorbent assay (ELISA), relying on a sandwich immunoassay between antibodi
Biological invasions are a major cause of biodiversity and ecosystem services loss.However, information on distribution and impacts is limited for many alien species, restricting the development of local management measures.The aim of this study is: to identify the current situation of the American bullfrog (Lithobates catesbeianus) invasion focus
The syphilis is a sexual transmitted disease, caused by the pal Treponema that has had an increment with the appearance of the syndrome of acquired immunodeficiency disease starting from 1980.In 1906 this germ was observed in the human cerebrospinal fluid, in this way it opened up the neurosiphilis diagnosis.Is presented the Drinks Stirrer case of